Why do PPIs fail for some people with LPR and GERD and even after doing everything "right"? In this episode, I'm joined by reflux researcher Dr. Nikki Johnston to break down the role of pepsin and non-acid reflux, the latest research on pepsin-targeted treatments, and practical ways to reduce pepsin exposure. 🙌
• Learn more about Dr. Nikki Johnston: https://www.nzymebio.com/
• Pepsin and Reflux Laboratory: https://www.mcw.edu/departments/ent-Ear-Nose-Throat/research/pepsin-and-reflux-laboratory
• Information on clinical trials: https://clinicaltrials.gov/study/NCT04383262
🤍 Looking for a 1:1 Personalized Approach to Overcoming Reflux? Apply to work 1:1 with FLORA Nutrition: https://www.mollypelletier.com/acid-reflux-specialist
🌱 Try our NATURAL Reflux Supplement: https://sequoiasoothe.com/
✨ What you’ll learn in this episode:
✔️ What pepsin is and how this digestive enzyme can damage your throat and esophagus
✔️ Why non-acid and weakly acidic reflux can still cause significant symptoms
✔️ The biggest misconceptions about pepsin that may be keeping patients stuck
✔️ What the latest pepsin research could mean for the future of LPR and GERD care
✔️ Practical, evidence-based ways to reduce your pepsin exposure at home
🌿 All of Molly's RECOMMENDED Products/Coffee Alternatives/Teas: https://www.mollypelletier.com/recommendedproducts
🌿 Resources & Support:
• Coaching & Resources: www.flora-nutrition.com
• Instagram: @mollypelletier.rd
• TikTok: @mollypelletier.RD
• Apply for coaching: https://www.mollypelletier.com/nutritioncounselingapplication
🙏 If this episode helped you better understand the role of pepsin, non-acid reflux, GERD, or LPR, share it with someone who needs to hear it—and don’t forget to follow and subscribe for more evidence-based reflux and gut-health strategies!
Chapters:
0:00 Intro
2:21 Why PPIs fall short
5:00 Pepsin's role and Nikki's research
9:45 Biggest misunderstandings about pepsin
13:01 Why pepsin is a target for treatment
16:02 What N-Zyme is working on
18:01 How to reduce pepsin exposure at home
20:31 Where to find Nikki and her work
21:14 Outro
Disclaimer: This podcast is for educational purposes only and not a substitute for personalized medical advice. Always consult your healthcare team before making changes to your routine.